Oral Ketone Supplementation Acutely Increases Markers of NLRP3 Inflammasome Activation in Human Monocytes
Neudorf H et al.
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Mol Nutr Food Res
Key finding
Acute ketone salt and ester ingestion increased markers of NLRP3 inflammasome activation, an unintended inflammatory effect.
What the study did
Two randomized double-blind placebo-controlled experiments in healthy adults. Study 1 gave ketone salts at 0.3 g BHB per kg to 10 males; study 2 gave a ketone monoester to 18 adults. Caspase-1 activation in monocytes increased after both supplements.
This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.