Ketone Monoester Plus Carbohydrate Supplementation Does Not Alter Exogenous and Plasma Glucose Oxidation or Metabolic Clearance Rate During Exercise in Men Compared with Carbohydrate Alone

Howard EE et al.

The Journal of nutrition

Key finding

Ketone monoester plus glucose did not change exogenous or plasma glucose oxidation compared with glucose alone, and it produced lower physical performance, including a 141 s slower 6.4 km time trial.

What the study did

In a randomized crossover study, 12 men consumed 573 mg/kg of ketone monoester plus 110 g glucose (KE+CHO) or 110 g glucose alone (CHO) before and during 90 minutes of steady-state treadmill exercise while wearing a weighted vest. Glucose oxidation and turnover were measured using indirect calorimetry and stable isotopes. Exogenous glucose oxidation, plasma glucose oxidation, and metabolic clearance rate did not differ between treatments, while glucose rate of appearance and disappearance were lower with KE+CHO. Time to exhaustion was 104 s shorter and the 6.4 km time trial was 141 s slower with KE+CHO.

This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.

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