β-Hydroxybutyrate Improves the Redox Status, Cytokine Production and Phagocytic Potency of Glucose-Deprived HMC3 Human Microglia-like Cells
Rana AK, Bhatt B, Kumar M
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Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Key finding
BHB supplementation restored redox status, mitochondrial health, cytokine secretion and phagocytic activity in glucose-deprived HMC3 microglia-like cells.
What the study did
In this in vitro study, HMC3 human microglia-like cells were exposed to glucose deprivation. The cells still proliferated but showed redox imbalance and mitochondrial dysfunction, reduced TNF and IL-1 beta secretion, and reduced phagocytic activity. Supplementation with beta-hydroxybutyrate (BHB) restored redox status, mitochondrial health, cytokine secretion and phagocytic activity in the glucose-deprived cells.
This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.