Feasibility and Tolerability of Ketogenic Interventions in Amyotrophic Lateral Sclerosis: A Dose-Finding Case Series
Herrmann C et al.
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Nutrients
Key finding
All ketogenic approaches raised blood BHB in ALS patients, but ketone salts caused significant GI side effects while the ester and diet were tolerated.
What the study did
Dose-finding case series in 9 ALS patients and 2 healthy subjects comparing ketone salts (KetoForce, 11.7 to 15.6 g BHB), a ketone ester (10 g BHB) and a ketogenic diet. The ester raised blood BHB to 2.2 to 2.7 mM versus 0.8 to 1.2 mM for salts. Salts caused diarrhea in 3 of 5 patients.
This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.