In this non-randomised interventional study, 21 participants with insulin-independent type 2 diabetes (14 men and 7 women, aged 45 plus or minus 11 years) wore glucose monitors for 6 weeks and took 25 ml of ketone monoester 3 times daily for 4 weeks, consuming 1,588 drinks in total. Adverse reactions were mild and infrequent, following fewer than 0.5 percent of drinks, and electrolytes, acid-base status and renal function stayed normal. Fructosamine fell from 335 to 290 micromol/L, mean daily glucose fell from 7.8 to 7.4 mM, and time in range rose from 67 percent to 69 percent, all p < .01.
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