Effects of Ketone Ester Supplementation on Cognition and Appetite in Individuals with and Without Metabolic syndrome: A Randomized Trial

Ten adults with metabolic syndrome and 10 without, matched for age, sex and race/ethnicity, took part in a randomized, single-blind, placebo-controlled crossover study. Cognitive function, subjective appetite and respiratory gases were measured at baseline and for 2 hours after a ketone ester or placebo drink, and food intake was recorded afterward. Regardless of group, indices of working memory improved (p of 0.035 or lower) and blood glucose decreased (p below 0.001) after the ketone ester.