Ketone ester/other
Human RCT
2022
Comparison of Exogenous Ketone Administration Versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial
Selvaraj S et al.
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding
The ketone ester drink was inferior to the ketogenic diet for achieving myocardial glucose suppression (44 percent versus 78 percent for the 24-hour diet and 83 percent for the 72-hour diet), while endogenous BHB predicted suppression with an AUROC of 0.88.
What the study did
KEETO-CROSS was a crossover, noninferiority trial in 20 healthy participants (18 completed all arms) comparing a weight-based ketone ester drink, a 24-hour ketogenic diet and a 72-hour ketogenic diet for achieving complete myocardial glucose suppression on 18F-FDG PET. Median beta-hydroxybutyrate was 3.82 mmol/L with the ketone ester drink, 0.77 with the 24-hour diet and 1.30 with the 72-hour diet. Complete suppression was achieved in 44 percent, 78 percent and 83 percent of participants respectively.
This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.