Brain glucose and ketone utilization in brain aging and neurodegenerative diseases

Kapogiannis D, Avgerinos KI

International review of neurobiology

Key finding

The review states that despite glucose hypometabolism brain cells can utilize ketones efficiently, which provides a rationale for ketogenic interventions in Alzheimer's disease and other neurodegenerative diseases.

What the study did

This review compares ketogenic interventions in the context of brain aging and neurodegenerative diseases, and discusses the potential of oral ketone ester for future therapeutic use. It describes how the aging brain and neurodegenerative disease involve inefficient glucose use, with glucose metabolism abnormalities identified by PET and magnetic resonance spectroscopy in aging and Alzheimer's disease.

This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.

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