Ketone ester/other
Animal
2025
β-Hydroxybutyrate Reduces Body Weight by Modulating Fatty Acid Oxidation and Beiging in the Subcutaneous Adipose Tissue of DIO Mice
Heras V, Mela V, Kompella P, Rojano E, Paz-Lopez G, et al.; senior author Moreno-Indias I
·
International Journal of Molecular Sciences
Key finding
BHB supplementation cut body weight in obese mice independent of food intake, acting through subcutaneous fat.
What the study did
Diet-induced obese mice were switched to a standard diet with or without BHB for six weeks. BHB mice lost significantly more weight without eating less. Their subcutaneous fat showed less adipocyte differentiation, lower PPARgamma protein, and changes in UCP1. Gene analysis showed more fatty acid activation and PPAR signaling.
This study used [form], not goBHB. It is shown here as general ketone science. Only goBHB studies back goBHB product claims.